DRAVPR ID  DRAVPR0155

Name   chCATH-B1

Sequence  VNTIIYNVGSTTISKYATFLNDLRNEAKDPSLKCYGIPMLPNTNTNPKYVLVELQGSNKKTITLMLRRNNLYVMGYSDPFETNKCRYHIFNDISGTERQDVETTLCPNANSRVSKNINFDSRYPTLESKAGVKSRSQVQLGIQILDSNIGKISGVMSFTEKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFNPNPKVLNLQETWGKISTAIHDAKNGVLPKPLELVDASGAKWIVLRVDEIKPDVALLNYV

Sequence Length  97

Source  the epithelium of the bursa of Fabricius, Gallus gallus

UniProt ID P10297

Gene PAP1

Target Organism  ZIKV,HIV-1

Activity 

• [Ref:10403789]ZIKV:similar to human cathelicidin against Zika virus, it directly Interact with the virus and TLR4/JNK/IRF3-Mediated Interferon Activation.HIV-1: Inhibits the replication of HIV-1 in human peripheral blood mononuclear cells with IC50 value of 14 nM

PDB ID  1D6A  1PAF 

Predicted Structure Download  No predicted structure information available for the entry

Modification  No modifications on the sequence.

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Literature 1

Title   Pokeweed antiviral protein isoforms PAP-I, PAP-II, and PAP-III depurinate RNA of human immunodeficiency virus (HIV)-1.

Pubmed ID   10403789

Author   Rajamohan F., Venkatachalam T.K., Irvin J.D., Uckun F.M.