General Information
DRAVPR ID DRAVPR0156
Name HB36.6
Sequence
Sequence Length 97
Source IAV(H1N1)
UniProt ID None
Gene HA
Activity Information
Target Organism IAV-H1N1
Activity [Ref;26845438]Influenza A/California/2009 (H1N1) IC50 = 0.18 µg/mL, A/Puerto Rico/1934 (H1N1) IC50 = 0.58 µg/mL, A/New Caledonia/1999 (H1N1) IC50 = 1.26 µg/mL, A/Hong Kong/2003 (H5N1) IC50 = 12 µg/mL
Structure Information
PDB ID None
Predicted Structure Download No predicted structure information available for the entry
Modification No modifications on the sequence.
Comment
These changes in the sequence make HB36.6 present a much higher affinity with the HA segment of the influenza virus than its precursor
Literature Information
Literature 1
Title A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response
Pubmed ID 26845438
Author P. S., Ward, A. B., Wilson, I. A., Dagley, A., Smee, D. F., Baker, D., & Fuller, D. H. (2016).