DRAVPR ID  DRAVPR0164

Name   Microcystis viridis lectin

Sequence  MASYKVNIPAGPLWSNAEAQQVGPKIAAAHQGNFTGQWTTVVESAMSVVEVELQVENTGIHEFKTDVLAGPLWSNDEAQKLGPQIAASYGAEFTGQWRTIVEGVMSVIQIKYTF

Sequence Length  114

Source  blue-green algae, Microcystis viridis

UniProt ID Q9RHG4

Gene mvl

Target Organism  HIV-1

Activity 

• [Ref:9210678]HIV-1:The antiviral activity of CV-N is due, at least in part, to unique, high-affinity interactions of CV-N with the viral surface envelope glycoprotein gp120. The biological activity of CV-N is highly resistant to physicochemical denaturation, further enhancing its potential as an anti-HIV microbicide.

PDB ID  1ZHQ, 1ZHS 

Predicted Structure Download  No predicted structure information available for the entry

Modification  No modifications on the sequence.

No comments found in the entry

Literature 1

Title   Isolation and characterization of a mannan-binding lectin from the freshwater cyanobacterium (blue-green algae) Microcystis viridis

Pubmed ID   9210678

Author   Boyd, M. R., Gustafson, K. R., McMahon, J. B., Shoemaker, R. H., O'Keefe, B. R., Mori, T., Gulakowski, R. J., Wu, L., Rivera, M. I., Laurencot, C. M., Currens, M. J., Cardellina, J. H., 2nd, Buckheit, R. W., Jr, Nara, P. L., Pannell, L. K., Sowder, R. C., 2nd, & Henderson, L. E. (1997).