To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPs037
Peptide Name SAH-HR2-D-PEG7-TC
Sequence DISGINASVVNI8KEIDRLXEVAKNLNESLIDLQELG(K*)
Sequence Length 38
Original Sequence DISGINASVVNIKEIDRLXEVAKNLNESLIDLQELG
Source Synthetic Construct
Validation Experimentally Validated
Activity Information
Target Organism SARS-CoV
Assay Pseudovirus Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target membrane
Mechanism Not Available
Structure Information
Linear/Cyclic Cyclic
N-terminal Modification Acetylation
C-terminal Modification Free
Special Amino Acid and Stapling Position Staple location is D and it is tricholeaterol with peg length is 7
Structure Description Not Available
Stereochemistry L
Literature Information
Literature 1
Title A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential
Pubmed ID 38177138
Reference Nat Commun. 2024 Jan 4;15(1):274.
Author Bird GH, Patten JJ, Zavadoski W, Barucci N, Godes M, Moyer BM, Owen CD, DaSilva-Jardine P, Neuberg DS, Bowen RA, Davey RA, Walensky LD.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.