Sequence information
DRAVP ID DRAVPc064
Name Imdevimab
Sequence Not available
Molecular Formula Not Available
Condition/Disease COVID-19
Group Approved
Type Antibody
Description Imdevimab is a monoclonal antibody combined with casirivimab in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. On November 21, 2020, the FDA authorized emergency approval of REGN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and older. Casirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this time, are not officially approved by the FDA. They are reserved for Emergency Use Authorization (EUA) only. In November 2021, the same indication was approved by the EMA.
Active sequence/Structure
External Links
DrugBank Accession Number DB15940
Pubchem ID 472422363
CHEMBL ID CHEMBL4650249
UNII 2Z3DQD2JHM
CAS 2415933-40-1
ClinicalTrails Information
NCT Number | Study Title | Condition/Disease | Status | Phase | Sponsor |
---|---|---|---|---|---|
NCT04790786 | UPMC OPTIMISE-C19 Trial, a COVID-19 Study (OPTIMISE-C19) | COVID-19 | Completed | Phase 4 | Erin McCreary |
NCT05502081 | Clinical Study to Compare Efficacy and Safety of Casirivimab and Imdevimab Combination, Remdesivir and Favipravir in Hospitalized COVID-19 Patients | COVID-19 | Completed | Phase 4 | Mansoura University Hospital |