General Information
DRAVP ID DRAVPe00305
Peptide Name Metalnikowin-1 (Metalnikowin I; Insects, animals)
Sequence VDKPDYRPRPRPPNM
Sequence Length 15
UniProt ID P80408
Source Palomena prasina (Green shield bug) (Cimex prasinus)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00305
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C80H128N26O22S
Absent amino acids ACEFGHILQSTW
Common amino acids P
Mass 1838.12
Pl 9.98
Basic residues 4
Acidic residues 2
Hydrophobic residues 1
Net charge 2
Boman Index -6814
Hydrophobicity -207.33
Aliphatic Index 19.33
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 106.43
Polar residues 2
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.