General Information
DRAVP ID DRAVPe00308
Peptide Name DASamP2(D74,derived from polybia-MPI)
Sequence IKWKKLLRAAKRIL
Sequence Length 14
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00308
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C83H149N25O15
Absent amino acids CDEFGHMNPQSTVY
Common amino acids K
Mass 1737.25
Pl 12.03
Basic residues 6
Acidic residues 0
Hydrophobic residues 8
Net charge 6
Boman Index -2149
Hydrophobicity -10.71
Aliphatic Index 153.57
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 423.08
Polar residues 0
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.