General Information
DRAVP ID DRAVPe00311
Peptide Name Apidaecin IA (insect)
Sequence GNNRPVYIPQPRPPHPRI
Sequence Length 18
UniProt ID P35581
Source Apis mellifera L
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00311
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C95H150N32O23
Absent amino acids ACDEFKLMSTW
Common amino acids P
Mass 2108.44
Pl 11.71
Basic residues 4
Acidic residues 0
Hydrophobic residues 3
Net charge 4
Boman Index -5356
Hydrophobicity -140.56
Aliphatic Index 59.44
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 87.65
Polar residues 4
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.