To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00314
Peptide Name Buforin II (toad)
Sequence TRSSRAGLQFPVGRVHRLLRK
Sequence Length 21
UniProt ID P55897
Source Synthetic construct(derived from buforin I after treatment with endoproteinase)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00314
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C106H184N40O26
Absent amino acids CDEIMNWY
Common amino acids R
Mass 2434.88
Pl 12.6
Basic residues 7
Acidic residues 0
Hydrophobic residues 7
Net charge 7
Boman Index -7021
Hydrophobicity -63.81
Aliphatic Index 88.1
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.