To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00316
Peptide Name Ponericin-L2 (ants, insects, animals)
Sequence LLKELWTKIKGAGKAVLGKIKGLL
Sequence Length 24
UniProt ID P82422
Source Pachycondyla goeldii (Ponerine ant)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00316
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C123H217N31O28
Absent amino acids CDFHMNPQRSY
Common amino acids KL
Mass 2578.27
Pl 10.3
Basic residues 6
Acidic residues 1
Hydrophobic residues 12
Net charge 5
Boman Index 1043
Hydrophobicity 39.58
Aliphatic Index 150.42
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 239.13
Polar residues 5
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.