General Information
DRAVP ID DRAVPe00333
Peptide Name GF-17−
Sequence GFNEIVQDIEDFLQNLV
Sequence Length 17
UniProt ID No entry found
Source Synthetic construct(derived from LL-37)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00333
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C90H137N21O30
Absent amino acids ACHKMPRSTWY
Common amino acids DEFILNQV
Mass 1993.2
Pl 3.43
Basic residues 0
Acidic residues 4
Hydrophobic residues 8
Net charge -4
Boman Index -2076
Hydrophobicity 12.94
Aliphatic Index 125.88
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.