General Information
DRAVP ID DRAVPe00346
Peptide Name D98 (frog,derived from temporin-LTc)
Sequence SLSRFLRFLKIVYRRAF
Sequence Length 17
UniProt ID No entry found
Source Synthetic construct(derived from temporin-LTc)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00346
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C104H166N30O21
Absent amino acids CDEGHMNPQTW
Common amino acids R
Mass 2172.65
Pl 12.01
Basic residues 5
Acidic residues 0
Hydrophobic residues 9
Net charge 5
Boman Index -3770
Hydrophobicity 32.35
Aliphatic Index 114.71
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 93.13
Polar residues 3
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.