General Information
DRAVP ID DRAVPe00347
Peptide Name Isracidin (cow)
Sequence RPKHPIKHQGLPQEVLNENLLRF
Sequence Length 23
UniProt ID No entry found
Source bovine colostrum
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00347
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C125H203N39O32
Absent amino acids ACDMSTWY
Common amino acids L
Mass 2764.23
Pl 9.99
Basic residues 6
Acidic residues 2
Hydrophobic residues 7
Net charge 4
Boman Index -5568
Hydrophobicity -98.7
Aliphatic Index 97.39
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.