To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00363
Peptide Name Caerin 1.1 mod 10(Caerin 1.1 [S4K;H12K,H16K,H24K])
Sequence GLLKVLGSVAKKVLPKVVPVIAEKL
Sequence Length 25
UniProt ID No entry found
Source Sythetic construct(derived from Caerin 1.1)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target virion envelope
Mechanism [Ref.26026377]Inhibit the infection of HIV by disrupting the HIV envelope and release viral core protein (p24).
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00363
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C124H224N30O29
Absent amino acids CDFHMNQRTWY
Common amino acids V
Mass 2599.33
Pl 10.18
Basic residues 5
Acidic residues 1
Hydrophobic residues 14
Net charge 4
Boman Index 2130
Hydrophobicity 98
Aliphatic Index 171.2
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Literature Information
Literature 1
Title VanCompernolle S, Smith PB, Bowie JH, Tyler MJ, Unutmaz D, Rollins-Smith LA.
Pubmed ID 26026377
Reference Peptides. 2015 Sep;71:296-303.
Author Inhibition of HIV infection by caerin 1 antimicrobial peptides.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.