General Information
DRAVP ID DRAVPe00366
Peptide Name Ctry2459-WT (Ctry2459, scorpions,animals)
Sequence FLGFLKNLF
Sequence Length 9
UniProt ID P0DMF3
Source Chaerilus tryznai (Scorpion)
Activity Information
Target Organism HCV
Assay
Activity
Hemolytic Activity
Cytotoxicity
Binding Target Not found
Mechanism The peptide potently destabilizes the viral structural integrity, thus reducing the initiation of HCV infection
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00366
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C57H83N11O11
Absent amino acids ACDEHIMPQRSTVWY
Common amino acids FL
Mass 1098.35
Pl 8.75
Basic residues 1
Acidic residues 0
Hydrophobic residues 6
Net charge 1
Boman Index 1245
Hydrophobicity 133.33
Aliphatic Index 130
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Literature Information
Literature 1
Title Design of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepatitis C virus.
Pubmed ID 23415044
Reference Biomaterials. 2013 Apr;34(13):3511-22.
Author Hong W, Zhang R, Di Z, He Y, Zhao Z, Hu J, Wu Y, Li W, Cao Z.