To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00413
Peptide Name HR2(1151-1185)
Sequence ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL
Sequence Length 35
UniProt ID P59594
Source Synthetic construct(derived from SARS-CoV spike protein)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C168H287N47O58
Absent amino acids CFHMPTWY
Common amino acids ILN
Mass 3893.41
Pl 4.36
Basic residues 3
Acidic residues 6
Hydrophobic residues 15
Net charge -3
Boman Index -5930
Hydrophobicity -8.29
Aliphatic Index 142
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 9
Literature Information
Literature 1
Title Fusion core structure of the severe acute respiratory syndrome coronavirus (SARS-CoV): in search of potent SARS-CoV entry inhibitors.
Pubmed ID 18442051
Reference J Cell Biochem. 2008 Aug 15;104(6):2335-47.
Author Chu LH, Chan SH, Tsai SN, Wang Y, Cheng CH, Wong KB, Waye MM, Ngai SM.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.