To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00458
Peptide Name P1
Sequence CNDFRSKTC
Sequence Length 9
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism Influenza viruse
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target membrane
Mechanism Avian influenza viruses possess two important surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA) against which neutralizing antibodies are produced. This peptide inhibits the replication of the virus in ovo and in vitro by its binding to the HA glycoprotein.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00458
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C42H68N14O15S2
Absent amino acids AEGHILMPQVWY
Common amino acids C
Mass 1073.21
Pl 8.06
Basic residues 2
Acidic residues 1
Hydrophobic residues 1
Net charge 1
Boman Index -3626
Hydrophobicity -101.11
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 125
Absorbance 280nm 15.63
Polar residues 5
Literature Information
Literature 1
Title A novel peptide inhibits the influenza virus replication by preventing the viral attachment to the host cells.
Pubmed ID 19680476
Reference Int J Biol Sci. 2009 Aug 8;5(6):543-8.
Author Rajik M, Omar AR, Ideris A, Hassan SS, Yusoff K.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.