General Information
DRAVP ID DRAVPe00841
Peptide Name 4(derived from FIV envelope glycoprotein )
Sequence LKAKTNISIREGPTLGNWAR
Sequence Length 20
UniProt ID P16090
Source Synthetic construct(derived from FIV envelope glycoprotein (gE))
Activity Information
Target Organism FIV
Assay Syncitia assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Syncytium formation
Mechanism The machanism might be peptide bound the surface of FIV permissive cells and were highly active in blocking FIV infection when administered before the virus.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00841
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C98H165N31O28
Absent amino acids CDFHMQVY
Common amino acids AGIKLNRT
Mass 2225.58
Pl 11
Basic residues 4
Acidic residues 1
Hydrophobic residues 7
Net charge 3
Boman Index -4206
Hydrophobicity -63
Aliphatic Index 88
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 289.47
Polar residues 7
Literature Information
Literature 1
Title Inhibition of feline immunodeficiency virus infection in vitro by envelope glycoprotein synthetic peptides.
Pubmed ID 8661378
Reference Virology. 1996 Jun 15;220(2):274-84.
Author Lombardi S, Massi C, Indino E, La Rosa C, Mazzetti P, Falcone ML, Rovero P, Fissi A, Pieroni O, Bandecchi P, Esposito F, Tozzini F, Bendinelli M, Garzelli C.