To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00856
Peptide Name 24(derived from FIV envelope glycoprotein )
Sequence CNSTKNLTFAMRSSGDYGEV
Sequence Length 20
UniProt ID P16090
Source Synthetic construct(derived from FIV envelope glycoprotein (gE))
Activity Information
Target Organism FIV
Assay Syncitia assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Syncytium formation
Mechanism The machanism might be peptide bound the surface of FIV permissive cells and were highly active in blocking FIV infection when administered before the virus.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00856
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C90H142N26O33S2
Absent amino acids HIPQW
Common amino acids S
Mass 2180.39
Pl 6.06
Basic residues 2
Acidic residues 2
Hydrophobic residues 4
Net charge 0
Boman Index -4550
Hydrophobicity -56.5
Aliphatic Index 39
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 78.42
Polar residues 11
Literature Information
Literature 1
Title Inhibition of feline immunodeficiency virus infection in vitro by envelope glycoprotein synthetic peptides.
Pubmed ID 8661378
Reference Virology. 1996 Jun 15;220(2):274-84.
Author Lombardi S, Massi C, Indino E, La Rosa C, Mazzetti P, Falcone ML, Rovero P, Fissi A, Pieroni O, Bandecchi P, Esposito F, Tozzini F, Bendinelli M, Garzelli C.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.