To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00905
Peptide Name T-112
Sequence VFPSDEFDASISQVNEKINQSLAFIRKSDELLHNV
Sequence Length 35
UniProt ID P69353
Source Synthetic construct(derived from Respiratory syncytial virus(RSV) fusion (F) protein)
Other Link DRAVPa1218
Activity Information
Target Organism RSV
Assay Cytopathic effect(CPE) assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00905
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C177H277N47O58
Absent amino acids CGMTWY
Common amino acids S
Mass 3991.43
Pl 4.58
Basic residues 4
Acidic residues 6
Hydrophobic residues 14
Net charge -2
Boman Index -7107
Hydrophobicity -28.86
Aliphatic Index 97.43
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 8
Literature Information
Literature 1
Title Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.
Pubmed ID 8700906
Reference Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2186-91.
Author Lambert DM, Barney S, Lambert AL, Guthrie K, Medinas R, Davis DE, Bucy T, Erickson J, Merutka G, Petteway SR Jr.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.