General Information
DRAVP ID DRAVPe01134
Peptide Name gB122(637-650)
Sequence HRRYFTFGGGYVYF
Sequence Length 14
UniProt ID P06437
Source Synthetic construct(derived from HSV-1 B glycoprotein (gB))
Activity Information
Target Organism HSV
Assay beta-galactosidase activity(Comprehensive antiviral assay)
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01134
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C87H112N22O19
Absent amino acids ACDEIKLMNPQSW
Common amino acids FGY
Mass 1769.98
Pl 9.7
Basic residues 3
Acidic residues 0
Hydrophobic residues 4
Net charge 3
Boman Index -2169
Hydrophobicity -38.57
Aliphatic Index 20.71
Half Life
Extinction Coefficient cystines 4470
Absorbance 280nm 343.85
Polar residues 7
Literature Information
Literature 1
Title Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection.
Pubmed ID 19104014
Reference Antimicrob Agents Chemother. 2009 Mar;53(3):987-96.
Author Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR.