General Information
DRAVP ID DRAVPe01142
Peptide Name gB122Δ1-3
Sequence RYFTFGGGYVYF
Sequence Length 12
UniProt ID P06437
Source Synthetic construct(derived from HSV-1 B glycoprotein (gB))
Activity Information
Target Organism HSV
Assay beta-galactosidase activity(Comprehensive antiviral assay)
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01142
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C75H93N15O17
Absent amino acids ACDEHIKLMNPQSW
Common amino acids FGY
Mass 1476.65
Pl 8.5
Basic residues 1
Acidic residues 0
Hydrophobic residues 4
Net charge 1
Boman Index -211
Hydrophobicity 19.17
Aliphatic Index 24.17
Half Life
Extinction Coefficient cystines 4470
Absorbance 280nm 406.36
Polar residues 7
Literature Information
Literature 1
Title Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection.
Pubmed ID 19104014
Reference Antimicrob Agents Chemother. 2009 Mar;53(3):987-96.
Author Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR.