General Information
DRAVP ID DRAVPe01145
Peptide Name gB122Δ10-15
Sequence GHRRYFTFG
Sequence Length 9
UniProt ID P06437
Taxon ID None
Source Synthetic construct(derived from HSV-1 B glycoprotein (gB))
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HSV
Assay beta-galactosidase activity(Comprehensive antiviral assay)
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01145
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C53H73N17O12
Absent amino acids ACDEIKLMNPQSVW
Common amino acids FGR
Mass 1140.27
Pl 10.84
Basic residues 3
Acidic residues 0
Hydrophobic residues 2
Net charge 3
Boman Index -2937
Hydrophobicity -104.44
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 186.25
Polar residues 4
Literature Information
Literature 1
Title Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection.
Pubmed ID 19104014
Reference Antimicrob Agents Chemother. 2009 Mar;53(3):987-96.
Author Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR.