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General Information
DRAVP ID DRAVPe01179
Peptide Name C18-c01P10A
Sequence GWWYKGRARAVSAVA
Sequence Length 15
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism H1N1
Assay Plaque assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target sialylgalactose
Mechanism The peptide has affinity for glycoconjugates on the cell surface. And its binding to the cell resulted in the significant inhibition of influenza virus infections.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01179
Linear/Cyclic Linear
N-terminal Modification Alkylated(C18)
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C78H116N24O18
Absent amino acids CDEFHILMNPQT
Common amino acids A
Mass 1677.93
Pl 11
Basic residues 3
Acidic residues 0
Hydrophobic residues 8
Net charge 3
Boman Index -1707
Hydrophobicity -13.33
Aliphatic Index 65.33
Half Life
Extinction Coefficient cystines 12490
Absorbance 280nm 892.14
Polar residues 4
Literature Information
Literature 1
Title Inhibition of influenza virus infections by sialylgalactose-binding peptides selected from a phage library.
Pubmed ID 19558186
Reference J Med Chem. 2009 Jul 23;52(14):4247-56.
Author Matsubara T, Sumi M, Kubota H, Taki T, Okahata Y, Sato T.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.