DRAVP ID  DRAVPe01219

Peptide Name   C6b(FIV ectodomain 770-775)

Sequence  WEDWVR

Sequence Length  6

UniProt ID  P16090 

Taxon ID  None

Source  Synthetic construct(derived from the Membrane-Proximal Ectodomain of Feline Immunodeficiency Virus)

Validation   Experimentally Validated

Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available

Target Organism  FIV

Assay  enzyme-linked immunosorbent assay(ELISA)

Activity 

• [Ref.12610147]FIV-M2(Feline immunodeficiency virus M2):inhibition of virus replication in MBM cells(IC50>50 µg/ml);
• FIV-Pet(Feline immunodeficiency virus Pet):inhibition of virus replication in MBM cells(IC50>50 µg/ml).

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not found

Mechanism  No machanism information found in the reference(s) presented in this entry

PDB ID  None

Predicted Structure Download  DRAVPe01219

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L

Literature 1

Title   Antiviral activity and conformational features of an octapeptide derived from the membrane-proximal ectodomain of the feline immunodeficiency virus transmembrane glycoprotein.

Pubmed ID   12610147

Reference   J Virol. 2003 Mar;77(6):3724-33.

Author   Giannecchini S, Di Fenza A, D'Ursi AM, Matteucci D, Rovero P, Bendinelli M.

DOI   10.1128/jvi.77.6.3724-3733.2003