General Information
DRAVP ID DRAVPe01221
Peptide Name C4a(FIV ectodomain 773-776)
Sequence WVRW
Sequence Length 4
UniProt ID P16090
Source Synthetic construct(derived from the Membrane-Proximal Ectodomain of Feline Immunodeficiency Virus)
Activity Information
Target Organism FIV
Assay enzyme-linked immunosorbent assay(ELISA)
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01221
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C33H43N9O5
Absent amino acids ACDEFGHIKLMNPQSTY
Common amino acids W
Mass 645.76
Pl 9.75
Basic residues 1
Acidic residues 0
Hydrophobic residues 3
Net charge 1
Boman Index -622
Hydrophobicity -52.5
Aliphatic Index 72.5
Half Life
Extinction Coefficient cystines 11000
Absorbance 280nm 3666.67
Polar residues 0
Literature Information
Literature 1
Title Antiviral activity and conformational features of an octapeptide derived from the membrane-proximal ectodomain of the feline immunodeficiency virus transmembrane glycoprotein.
Pubmed ID 12610147
Reference J Virol. 2003 Mar;77(6):3724-33.
Author Giannecchini S, Di Fenza A, D'Ursi AM, Matteucci D, Rovero P, Bendinelli M.