To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01282
Peptide Name a-p9
Sequence LMRIRQMMT
Sequence Length 9
UniProt ID No entry found
Taxon ID None
Source Synthetic construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not available
Activity Information
Target Organism PRRSV
Assay MTT assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target PRRSV polymerase
Mechanism PRRSV polymerase is an RNA-dependent RNA polymerase and is an enzyme specific to viruses, RNA-dependent RNA polymerase is one of the most important proteins for intracellular replication of viruses.The peptide could exert antiviral activity by inhibiting polymerase.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01282
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C48H90N16O12S3
Absent amino acids ACDEFGHKNPSVWY
Common amino acids M
Mass 1179.52
Pl 12
Basic residues 2
Acidic residues 0
Hydrophobic residues 2
Net charge 2
Boman Index -2106
Hydrophobicity 8.89
Aliphatic Index 86.67
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Literature Information
Literature 1
Title Antiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro.
Pubmed ID 22743126
Reference Virology. 2012 Oct 10;432(1):73-80.
Author Liu K, Feng X, Ma Z, Luo C, Zhou B, Cao R, Huang L, Miao D, Pang R, He D, Lian X, Chen P.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.