To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01350
Peptide Name H2-(1-15)
Sequence ECRSTSYAGAVVNDL
Sequence Length 15
UniProt ID P10224
Source Synthetic construct(derived from HSV ribonucleotide reductase subunit 2)
Activity Information
Target Organism HSV
Assay Ribonucleotide reductase assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target ribonucleotide reductase
Mechanism The peptide inhibits the activity of ribonucleotide rductase.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01350
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C65H105N19O25S
Absent amino acids FHIKMPQW
Common amino acids ASV
Mass 1584.72
Pl 4.37
Basic residues 1
Acidic residues 2
Hydrophobic residues 5
Net charge -1
Boman Index -2776
Hydrophobicity -4.67
Aliphatic Index 78
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 106.43
Polar residues 7
Literature Information
Literature 1
Title Structure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase.
Pubmed ID 3040743
Reference J Biol Chem. 1987 Sep 15;262(26):12413-6.
Author Gaudreau P, Michaud J, Cohen EA, Langelier Y, Brazeau P.
DOI Not available
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.