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General Information
DRAVP ID DRAVPe01380
Peptide Name D4C3
Sequence FRFKIKFRLKFRFKARFKFRAKFRA
Sequence Length 25
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism FIV
Assay reverse transcriptase (RT) assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism The peptide may facilitate interference with viral assembly or release and reduce the number of infectious progeny virions.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01380
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C165H255N49O26
Absent amino acids CDEGHMNPQSTVWY
Common amino acids F
Mass 3341.15
Pl 12.71
Basic residues 12
Acidic residues 0
Hydrophobic residues 13
Net charge 12
Boman Index -8371
Hydrophobicity -57.2
Aliphatic Index 43.2
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro.
Pubmed ID 12208971
Reference J Virol. 2002 Oct;76(19):9952-61.
Author Ma J, Kennedy-Stoskopf S, Jaynes JM, Thurmond LM, Tompkins WA.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.