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General Information
DRAVP ID DRAVPe01386
Peptide Name D1A22
Sequence FLFAFRIFKRVFKKFRKLFKRAF
Sequence Length 23
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism FIV
Assay reverse transcriptase (RT) assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism The peptide may facilitate interference with viral assembly or release and reduce the number of infectious progeny virions.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01386
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C155H234N40O24
Absent amino acids CDEGHMNPQSTWY
Common amino acids F
Mass 3041.82
Pl 12.49
Basic residues 9
Acidic residues 0
Hydrophobic residues 14
Net charge 9
Boman Index -4117
Hydrophobicity 20.87
Aliphatic Index 72.17
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro.
Pubmed ID 12208971
Reference J Virol. 2002 Oct;76(19):9952-61.
Author Ma J, Kennedy-Stoskopf S, Jaynes JM, Thurmond LM, Tompkins WA.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.