General Information
DRAVP ID DRAVPe01392
Peptide Name D5D
Sequence AVKRVGRRLKKLARKIARLGVAF
Sequence Length 23
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism FIV
Assay reverse transcriptase (RT) assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism The peptide may facilitate interference with viral assembly or release and reduce the number of infectious progeny virions.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01392
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C118H216N42O24
Absent amino acids CDEHMNPQSTWY
Common amino acids R
Mass 2607.28
Pl 12.61
Basic residues 9
Acidic residues 0
Hydrophobic residues 12
Net charge 9
Boman Index -5290
Hydrophobicity -1.74
Aliphatic Index 123.04
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Literature Information
Literature 1
Title Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro.
Pubmed ID 12208971
Reference J Virol. 2002 Oct;76(19):9952-61.
Author Ma J, Kennedy-Stoskopf S, Jaynes JM, Thurmond LM, Tompkins WA.