General Information
DRAVP ID DRAVPe01417
Peptide Name SARSWW-II(864-886)
Sequence ATAGWTFGAGAALQIPFAMQMAY
Sequence Length 23
UniProt ID P11224
Source Synthetic construct(derived from SARS-CoV spike protein)
Activity Information
Target Organism SARS-CoV
Assay Plaque formation assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target membrane
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01417
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C110H160N26O29S2
Absent amino acids CDEHKNRSV
Common amino acids A
Mass 2374.76
Pl 5.57
Basic residues 0
Acidic residues 0
Hydrophobic residues 12
Net charge 0
Boman Index 2196
Hydrophobicity 73.48
Aliphatic Index 64.35
Half Life
Extinction Coefficient cystines 6990
Absorbance 280nm 317.73
Polar residues 6
Literature Information
Literature 1
Title Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein
Pubmed ID 16616792
Reference Virus Res. 2006 Sep;120(1-2):146-55.
Author Sainz B Jr, Mossel EC, Gallaher WR, Wimley WC, Peters CJ, Wilson RB, Garry RF.