General Information
DRAVP ID DRAVPe01418
Peptide Name SARSWW-III(1028-1049)
Sequence GYHLMSFPQAAPHGVVFLHVTW
Sequence Length 22
UniProt ID P11224
Source Synthetic construct(derived from SARS-CoV spike protein)
Activity Information
Target Organism SARS-CoV
Assay Plaque formation assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target membrane
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01418
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C120H168N30O27S
Absent amino acids CDEIKNR
Common amino acids HV
Mass 2494.9
Pl 7.02
Basic residues 3
Acidic residues 0
Hydrophobic residues 10
Net charge 3
Boman Index 1247
Hydrophobicity 47.73
Aliphatic Index 84.09
Half Life
Extinction Coefficient cystines 6990
Absorbance 280nm 332.86
Polar residues 5
Literature Information
Literature 1
Title Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein
Pubmed ID 16616792
Reference Virus Res. 2006 Sep;120(1-2):146-55.
Author Sainz B Jr, Mossel EC, Gallaher WR, Wimley WC, Peters CJ, Wilson RB, Garry RF.