General Information
DRAVP ID DRAVPe01419
Peptide Name SARSWW-IV(1075-1093)
Sequence GVFVFNGTSWFITQRNFFS
Sequence Length 19
UniProt ID P11224
Source Synthetic construct(derived from SARS-CoV spike protein)
Activity Information
Target Organism SARS-CoV
Assay Plaque formation assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target membrane
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01419
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C109H148N26O27
Absent amino acids ACDEHKLMPY
Common amino acids F
Mass 2254.53
Pl 9.75
Basic residues 1
Acidic residues 0
Hydrophobic residues 9
Net charge 1
Boman Index -1357
Hydrophobicity 37.89
Aliphatic Index 51.05
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 305.56
Polar residues 8
Literature Information
Literature 1
Title Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein
Pubmed ID 16616792
Reference Virus Res. 2006 Sep;120(1-2):146-55.
Author Sainz B Jr, Mossel EC, Gallaher WR, Wimley WC, Peters CJ, Wilson RB, Garry RF.