To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01420
Peptide Name SARSWW-Vb(1169-1194)
Sequence AACEVAKNLNESLIDLQELGKYEQYIKW
Sequence Length 28
UniProt ID P11224
Source Synthetic construct(derived from SARS-CoV spike protein)
Activity Information
Target Organism SARS-CoV
Assay Plaque formation assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target membrane
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01420
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C147H230N36O46S
Absent amino acids FHMPRT
Common amino acids EL
Mass 3269.72
Pl 4.59
Basic residues 3
Acidic residues 5
Hydrophobic residues 11
Net charge -2
Boman Index -3711
Hydrophobicity -41.43
Aliphatic Index 104.64
Half Life
Extinction Coefficient cystines 8480
Absorbance 280nm 314.07
Polar residues 7
Literature Information
Literature 1
Title Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein
Pubmed ID 16616792
Reference Virus Res. 2006 Sep;120(1-2):146-55.
Author Sainz B Jr, Mossel EC, Gallaher WR, Wimley WC, Peters CJ, Wilson RB, Garry RF.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.