To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01421
Peptide Name MHVWW-IV(1144-1162)
Sequence GYFVQDDGEWKFTGSSYYY
Sequence Length 19
UniProt ID P11224
Source Synthetic construct(derived from MHV spike protein)
Activity Information
Target Organism SARS-CoV
Assay Plaque formation assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target membrane
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01421
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C110H138N22O34
Absent amino acids ACHILMNPR
Common amino acids Y
Mass 2312.43
Pl 4.03
Basic residues 1
Acidic residues 3
Hydrophobic residues 4
Net charge -2
Boman Index -3012
Hydrophobicity -93.16
Aliphatic Index 15.26
Half Life
Extinction Coefficient cystines 11460
Absorbance 280nm 636.67
Polar residues 10
Literature Information
Literature 1
Title Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein
Pubmed ID 16616792
Reference Virus Res. 2006 Sep;120(1-2):146-55.
Author Sainz B Jr, Mossel EC, Gallaher WR, Wimley WC, Peters CJ, Wilson RB, Garry RF.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.