General Information
DRAVP ID DRAVPe01531
Peptide Name LL-23
Sequence LLGDLLRKSKEKIGKEFKRIVQR
Sequence Length 23
UniProt ID No entry found
Source Synthetic construct(derived from human cathelicidin LL-37)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01531
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C124H220N38O32
Absent amino acids ACHMNPTWY
Common amino acids K
Mass 2755.35
Pl 10.55
Basic residues 8
Acidic residues 3
Hydrophobic residues 8
Net charge 5
Boman Index -6537
Hydrophobicity -75.65
Aliphatic Index 114.35
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Literature Information
Literature 1
Title Anti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins.
Pubmed ID 18591279
Reference Antimicrob Agents Chemother. 2008 Sep;52(9):3438-40.
Author Wang G, Watson KM, Buckheit RW Jr.