General Information
DRAVP ID DRAVPe01538
Peptide Name GF-17d1
Sequence GFKRIVQRiKDFLRNLV
Sequence Length 17
UniProt ID No entry found
Taxon ID None
Source Synthetic construct(derived from human cathelicidin LL-37)
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry Mixed(D-Ile9)
Physicochemical Information
Formula C91H151N29O20
Absent amino acids ACEHMPSTWY
Common amino acids R
Mass 2102.56
Pl 11.72
Basic residues 5
Acidic residues 1
Hydrophobic residues 7
Net charge 4
Boman Index -4702
Hydrophobicity -35.88
Aliphatic Index 102.94
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Literature Information
Literature 1
Title Anti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins.
Pubmed ID 18591279
Reference Antimicrob Agents Chemother. 2008 Sep;52(9):3438-40.
Author Wang G, Watson KM, Buckheit RW Jr.