General Information
DRAVP ID DRAVPe01554
Peptide Name Dermaseptin-1
Sequence ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Sequence Length 34
Source Phyllomedusa sauvagei (Sauvage's leaf frog)
Activity Information
Target Organism CCV,FV3
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01554
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C152H257N43O44S2
Absent amino acids CEFNPRVY
Common amino acids A
Mass 3455.09
Pl 10
Basic residues 5
Acidic residues 1
Hydrophobic residues 15
Net charge 4
Boman Index -555
Hydrophobicity 18.53
Aliphatic Index 92.35
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 166.67
Polar residues 9
Literature Information
Literature 1
Title Inactivation of viruses infecting ectothermic animals by amphibian and piscine antimicrobial peptides.
Pubmed ID 15193922
Reference Virology. 2004 Jun 1;323(2):268-75.
Author Chinchar VG, Bryan L, Silphadaung U, Noga E, Wade D, Rollins-Smith L.