To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01575
Peptide Name TAT(48-57)[Q7R]
Sequence GRKKRRRRRR
Sequence Length 10
UniProt ID P04610
Source Synthetic construct
Activity Information
Target Organism HIV
Assay infection inhibition assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01575
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C56H113N33O11
Absent amino acids ACDEFHILMNPQSTVWY
Common amino acids R
Mass 1424.73
Pl 12.78
Basic residues 9
Acidic residues 0
Hydrophobic residues 0
Net charge 9
Boman Index -11460
Hydrophobicity -397
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Literature Information
Literature 1
Title Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat.
Pubmed ID 22319541
Reference Int J Pept. 2012;2012:349427.
Author Keogan S, Passic S, Krebs FC.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.