To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01633
Peptide Name 7R-Ahx-HBV Large envelope protein (219-243)
Sequence RRRRRRRXPTSNHSPTSCPPTCPGYRWMCLRRF
Sequence Length 33
UniProt ID P03138
Source Synthetic construct
Activity Information
Target Organism HBV
Assay FQ-PCR
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target DNA
Mechanism The peptide can efficiently enter cells and inhibit the envelopment of HBV nucleocapsids and subsequent secretion of viral particles.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification The 'X' at position 8 is 6-aminocaproic acid.
Stereochemistry L
Physicochemical Information
Formula C167H270N66O40S4
Absent amino acids ADEIKQV
Common amino acids R
Mass 4099.99
Pl 12
Basic residues 11
Acidic residues 0
Hydrophobic residues 3
Net charge 11
Boman Index -16119
Hydrophobicity -153.94
Aliphatic Index 11.82
Half Life
Extinction Coefficient cystines 7115
Absorbance 280nm 222.34
Polar residues 12
Literature Information
Literature 1
Title Artificial recombinant cell-penetrating peptides interfere with envelopment of hepatitis B virus nucleocapsid and viral production.
Pubmed ID 21144865
Reference Antiviral Res. 2011 Jan;89(1):109-14.
Author Pan XB, Wei L, Han JC, Ma H, Deng K, Cong X.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.