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General Information
DRAVP ID DRAVPe01634
Peptide Name 7R-Ahx-P3
Sequence RRRRRRRXGSLLGRMKGA
Sequence Length 18
UniProt ID None
Source Synthetic construct
Activity Information
Target Organism HBV
Assay FQ-PCR
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target DNA
Mechanism The peptide can efficiently enter cells and inhibit the envelopment of HBV nucleocapsids and subsequent secretion of viral particles.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification The 'X' at position 8 is 6-aminocaproic acid.
Stereochemistry L
Physicochemical Information
Formula C83H158N42O18S
Absent amino acids CDEFHINPQTVWY
Common amino acids R
Mass 2193.84
Pl 12.85
Basic residues 9
Acidic residues 0
Hydrophobic residues 3
Net charge 9
Boman Index -11149
Hydrophobicity -170
Aliphatic Index 48.89
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Literature Information
Literature 1
Title Artificial recombinant cell-penetrating peptides interfere with envelopment of hepatitis B virus nucleocapsid and viral production.
Pubmed ID 21144865
Reference Antiviral Res. 2011 Jan;89(1):109-14.
Author Pan XB, Wei L, Han JC, Ma H, Deng K, Cong X.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.