To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01636
Peptide Name 7R-Ahx-HBV Large envelope protein (96-116)
Sequence RRRRRRRXPLSPPLRNTHPQAMQWNSTTF
Sequence Length 29
UniProt ID P03138
Source Synthetic construct
Activity Information
Target Organism HBV
Assay FQ-PCR
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target DNA
Mechanism The peptide can efficiently enter cells and inhibit the envelopment of HBV nucleocapsids and subsequent secretion of viral particles.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification The 'X' at position 8 is 6-aminocaproic acid.
Stereochemistry L
Physicochemical Information
Formula C150H245N59O37S
Absent amino acids CDEGIKVY
Common amino acids R
Mass 3628.37
Pl 12.85
Basic residues 9
Acidic residues 0
Hydrophobic residues 5
Net charge 9
Boman Index -14358
Hydrophobicity -172.76
Aliphatic Index 30.34
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 196.43
Polar residues 7
Literature Information
Literature 1
Title Artificial recombinant cell-penetrating peptides interfere with envelopment of hepatitis B virus nucleocapsid and viral production.
Pubmed ID 21144865
Reference Antiviral Res. 2011 Jan;89(1):109-14.
Author Pan XB, Wei L, Han JC, Ma H, Deng K, Cong X.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.