To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01716
Peptide Name JEV Ep (401–428)
Sequence STLGKAFSTTLKGAQRLAALGDTAWDFG
Sequence Length 28
UniProt ID P0DOH7
Source Synthetic construct
Activity Information
Target Organism JEV
Assay qRT-PCR, western blotting, the plaque assay, immunofluorescence analysis
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target membrane
Mechanism Peptide derived from protein E stem may inhibit virus infection by blocking virus entry.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C129H203N35O40
Absent amino acids CEHIMNPVY
Common amino acids A
Mass 2884.24
Pl 8.31
Basic residues 3
Acidic residues 2
Hydrophobic residues 12
Net charge 1
Boman Index -2530
Hydrophobicity 0.36
Aliphatic Index 73.57
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 203.7
Polar residues 10
Literature Information
Literature 1
Title Antiviral activity of peptide inhibitors derived from the protein E stem against Japanese encephalitis and Zika viruses.
Pubmed ID 28232248
Reference Antiviral Res. 2017 May;141:140-149.
Author Chen L, Liu Y, Wang S, Sun J, Wang P, Xin Q, Zhang L, Xiao G, Wang W.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.