To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01721
Peptide Name ZIKV Ep (424-452)
Sequence AWDFGSVGGVFNSLGKGIHQIFGAAFKSL
Sequence Length 29
UniProt ID Q32ZE1
Source Synthetic construct
Activity Information
Target Organism ZIKV
Assay qRT-PCR, western blotting, the plaque assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target membrane
Mechanism Peptide derived from protein E stem may inhibit virus infection by blocking virus entry.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C142H208N36O37
Absent amino acids CEMPRTY
Common amino acids G
Mass 3011.43
Pl 8.64
Basic residues 3
Acidic residues 1
Hydrophobic residues 14
Net charge 2
Boman Index 622
Hydrophobicity 49.66
Aliphatic Index 84.14
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 196.43
Polar residues 10
Literature Information
Literature 1
Title Antiviral activity of peptide inhibitors derived from the protein E stem against Japanese encephalitis and Zika viruses.
Pubmed ID 28232248
Reference Antiviral Res. 2017 May;141:140-149.
Author Chen L, Liu Y, Wang S, Sun J, Wang P, Xin Q, Zhang L, Xiao G, Wang W.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.