To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01727
Peptide Name SARS-CoV-S (215-232), peptide 9626
Sequence TLKPIFKLPLGINITNFR
Sequence Length 18
UniProt ID P59594
Source Synthetic construct
Activity Information
Target Organism SARS-CoV PsV
Assay western blot
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target not found
Mechanism Presumably inhibit virus entry by binding to Spike protein, hACE2, or an unknown co-receptor.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C100H165N25O23
Absent amino acids ACDEHMQSVWY
Common amino acids IL
Mass 2085.56
Pl 11.17
Basic residues 3
Acidic residues 0
Hydrophobic residues 8
Net charge 3
Boman Index -802
Hydrophobicity 34.44
Aliphatic Index 130
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Literature Information
Literature 1
Title Identification of a new region of SARS-CoV S protein critical for viral entry.
Pubmed ID 19853613
Reference J Mol Biol. 2009 Dec 11;394(4):600-5.
Author Guo Y, Tisoncik J, McReynolds S, Farzan M, Prabhakar BS, Gallagher T, Rong L, Caffrey M.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.