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General Information
DRAVP ID DRAVPe01821
Peptide Name BPIP
Sequence LLMVNEATRFQTVSGFV
Sequence Length 17
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism SARS-CoV-2
Assay MBP-tagged (SARS-CoV-2) assay
Activity
Hemolytic Activity
Cytotoxicity
Binding Target Mpro
Mechanism The peptide inhibits Mpro, a protein crucial for viral replication.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C86H138N22O25S
Absent amino acids CDHIKPWY
Common amino acids V
Mass 1912.23
Pl 6
Basic residues 1
Acidic residues 1
Hydrophobic residues 8
Net charge 0
Boman Index -943
Hydrophobicity 70
Aliphatic Index 102.94
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Literature Information
Literature 1
Title A ricin-based peptide BRIP from Hordeum vulgare inhibits Mpro of SARS-CoV-2
Pubmed ID 35896605
Reference Sci Rep. 2022 Jul 27;12(1):12802
Author Kashyap P, Bhardwaj VK, Chauhan M, Chauhan V, Kumar A, Purohit R, Kumar A, Kumar S
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.