To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01821
Peptide Name BPIP
Sequence LLMVNEATRFQTVSGFV
Sequence Length 17
UniProt ID No entry found
Taxon ID None
Source Synthetic construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV-2
Assay MBP-tagged (SARS-CoV-2) assay
Activity
Hemolytic Activity
Cytotoxicity
Binding Target Mpro
Mechanism The peptide inhibits Mpro, a protein crucial for viral replication.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C86H138N22O25S
Absent amino acids CDHIKPWY
Common amino acids V
Mass 1912.23
Pl 6
Basic residues 1
Acidic residues 1
Hydrophobic residues 8
Net charge 0
Boman Index -943
Hydrophobicity 70
Aliphatic Index 102.94
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Literature Information
Literature 1
Title A ricin-based peptide BRIP from Hordeum vulgare inhibits Mpro of SARS-CoV-2
Pubmed ID 35896605
Reference Sci Rep. 2022 Jul 27;12(1):12802
Author Kashyap P, Bhardwaj VK, Chauhan M, Chauhan V, Kumar A, Purohit R, Kumar A, Kumar S
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.