To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01825
Peptide Name TP1
Sequence MRRKVELFTYMRFD
Sequence Length 14
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism EV-A71
Assay cell protection assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism The peptide could associate with the cellular receptors at the surface of cells and prevented the attachment of EV-A71 to the cellular receptors.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification Free
Stereochemistry L
Physicochemical Information
Formula C85H134N24O21S2
Absent amino acids ACGHINPQSW
Common amino acids R
Mass 1892.27
Pl 9.98
Basic residues 4
Acidic residues 2
Hydrophobic residues 4
Net charge 2
Boman Index -4893
Hydrophobicity -64.29
Aliphatic Index 48.57
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 114.62
Polar residues 2
Literature Information
Literature 1
Title Stability and antiviral activity of SP41 peptide in human serum.
Pubmed ID 34314773
Reference Virus Res. 2021 Oct 2;303:198456.
Author Zarif F, Anasir MI, Koh JX, Chew MF, Poh CL.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.