To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01873
Peptide Name FP8
Sequence WLVFFVRRKK
Sequence Length 10
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism Influenza virus
Assay Plaque reduction assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target HA
Mechanism the mechanism whereby FluPep mediates its antiviral effects is likely to involve inhibiting the binding of HA to sialic acid receptors or through interference with the fusion process by blocking protease cleavage.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C69H107N19O11
Absent amino acids ACDEGHIMNPQSTY
Common amino acids FKRV
Mass 1378.73
Pl 12.02
Basic residues 4
Acidic residues 0
Hydrophobic residues 6
Net charge 4
Boman Index -1965
Hydrophobicity 1
Aliphatic Index 97
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 611.11
Polar residues 0
Literature Information
Literature 1
Title A novel family of peptides with potent activity against influenza A viruses.
Pubmed ID 22258859
Reference J Gen Virol. 2012 May;93(Pt 5):980-986.
Author Nicol MQ, Ligertwood Y, Bacon MN, Dutia BM, Nash AA.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.