General Information


DRAVP ID  DRAVPe01875

Peptide Name   HPV-31 L1 Cta

Sequence  GYRARPKFKAGKR

Sequence Length  13

UniProt ID  No entry found

Source  Synthetic construct



Activity Information


Target Organism  HPV

Assay  luminescence assay

Activity 

  • [Ref.15170645]human papillomavirus(HPV):inhibition of HPV virus-like particle cell entry(86±3% inhibition at 10 μg/ml); inhibition of pseudovirions infection(91±4% inhibition at 10 μg/ml).

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity 

  • No cytotoxicity information or data found in the reference(s) presented in this entry

Binding Target  Not found

Mechanism  No mechanism information found in the reference(s).



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  C69H115N25O15

Absent amino acids  CDEHILMNQSTVW

Common amino acids  KR

Mass  1534.83

Pl  11.74

Basic residues  6

Acidic residues  0

Hydrophobic residues  3

Net charge  6

Boman Index  -5307

Hydrophobicity  -173.08

Aliphatic Index  15.38

Half Life 

  •     Mammalian:30 hour
  •     Yeast:>20 hour
  •     E.coli:>10 hour

Extinction Coefficient cystines  1490

Absorbance 280nm  124.17

Polar residues  3



Literature Information


Literature 1

Title   Positively charged synthetic peptides from structural proteins of papillomaviruses abrogate human papillomavirus infectivity.

Pubmed ID   15170645

Reference   J Med Virol. 2004 Jul;73(3):474-80.

Author   Bousarghin L, Touzé A, Yvonnet B, Coursaget P.

DOI   10.1002/jmv.20114